ISSN: 2223-2133 (Online), 1815-8986 (Print)
Vol 4. Number 2, December 2004
Observations on the nuclear chromatin pattern in cells of a case of canine circumanal gland adenoma in Trinidad
G. Isitor, J. Cooper
An incidence of canine circumanal gland adenoma (CGA) is reported, apparently for the first time, in the island of Trinidad and Tobago. The case involved an ll-year-old Rottweiler dog which was presented in relatively good health except for noticeable masses around the perianal region. Apart from routine histopathological investigation which enabled a definitive diagnosis of CGA with secondary vascularization, analysis of the nuclear chromatin texture was performed on the digitalized images of both reserve and hepatoid cells of the neoplasm. The mean nuclear pixel intensity value of the images of processed CGA reserve cells was significantly lower than those of the processed CGA hepatoid cells (P<O.I). Our observation based on the texture analytical data suggests a high degree of rate of multiplication of the reserve cells at the expense of degenerating hepatoid cells. The relevance of this finding is discussed within the context of vascular supply to the neoplastic cells.